Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease
نویسندگان
چکیده
منابع مشابه
Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease.
The macrophage, a versatile cell type prominently involved in host defense and immunity, assumes a distinct state of alternative activation in the context of polarized type 2 immune responses such as allergic inflammation and helminth infection. This alternatively activated phenotype is induced by the canonical type 2 cytokines interleukin (IL)-4 and IL-13, which mediate expression of several c...
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ژورنال
عنوان ژورنال: Annual Review of Immunology
سال: 2013
ISSN: 0732-0582,1545-3278
DOI: 10.1146/annurev-immunol-032712-095906